Muricidal suppression by histidine and its antagonism by α-fluoromethylhistidine, a suicide inhibitor of histidine decarboxylase
نویسندگان
چکیده
منابع مشابه
A Rapid Histidine Decarboxylase Assay1
Histidine decarboxylase (EC 4.1.1.22) catalyzes the conversion of histidine to histamine. Because current assays for enzyme activity are time consuming and require additional enzymes or large amounts of tissue, a rapid radioisotopic assay was devised. Using commercially available radioactive histidine (without additional purification), the enzyme mediates the formation of histamine. The product...
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epoxyquinomicins A, B, C, and D, respectively. Therefore, these epoxyquinomicins are unique candidates for antiinflammatory agents. The modeof action appears to be different from that of common NSAIDs(non-steroidal antiinflammatory drugs)3), since epoxyquinomicins C and D did not inhibit cyclooxygenase-1 at the concentration of 300 /iu. The mechanism of the antiarthritic effect has not been elu...
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With a modification of Taylor's decarboxylation broth, histidine decarboxylase was detected in Enterobacter aerogenes, Morganella morganii, Raoultella ornithinolytica, and some strains of Citrobacter youngae and Raoultella planticola. This method provides a useful confirmatory test for identification of E. aerogenes strains.
متن کاملHistidine Decarboxylase in Hyaline Membrane
During the latter part of pregnancy, the foetal rat produces large quantities of histamine which may be concerned with the growth of the foetus (Kahlson and Rosengren, 1959). Kahlson (1960) reported increased formation of histamine by the human foetus as well: recently Davis (1961) suggested that the antagonism of such excess histamine might account for the beneficial effect of an antihistamine...
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the main purpose of this research was to:1.develop a coking model for thermal cracking of naphtha.2.study coke inhibition methods using different coke inhibitors.developing a coking model in naphtha cracking reactors requires a suitable model of the thermal cracking reactor based on a reliable kinetic model.to obtain reliable results all these models shall be solved simultaneously.for this pu...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1984
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)62531-x